Function Deficiency of RbAp48 protein and memory loss

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cartoon representation of molecular structure of protein 1p22, belongs wd40 repeat


rbap48, known rbbp4 gene encodes nuclear protein, belongs highly conserved family of wd40 repeat. gene present in many protein complexes involved in histone acetylation , deacetylation processes chromatin assembly. gene belongs mi-2/nurd complex, known nucleosome remodeling deacetylase complex plays role in both atp-dependent chromatin remodeling , histone deacetylase activities. protein part of co-repressor complex important component of transcriptional silencing. gene available , can found in several cellular proteins bind directly retinoblastoma protein regulate growth , cell proliferation. protein found in transcriptional repression of e2f-responsive genes, group of genes encode family of transcription factors.








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