Research Prasterone

1 research

1.1 anabolic uses

1.1.1 body composition


1.2 cancer
1.3 cardiovascular disease
1.4 drug addiction
1.5 lupus
1.6 memory
1.7 mood

1.7.1 strength

research
anabolic uses
body composition

a meta-analysis of intervention studies shows prasterone supplementation in elderly men can induce small significant positive effect on body composition strictly dependent on prasterone conversion bioactive metabolites such androgens or estrogens.

cancer

there no evidence prasterone of benefit in treating or preventing cancer. although prasterone postulated inhibitor towards glucose-6-phosphate dehydrogenase (g6pd) , suppresses leukemia cell proliferation in vitro, prasterone may enhance g6pd mrna expression, confounding inhibitory effects.

cardiovascular disease

a review in 2003 found then-extant evidence sufficient suggest low serum levels of dhea-s may associated coronary heart disease in men, insufficient determine whether prasterone supplementation have cardiovascular benefit.

drug addiction

a double-blind, placebo-controlled study in adult polydrug users in detoxification program showed efficacy of prasterone treatment combined psychosocial enrichment , after-care. prasterone administration positively affected decision-making, mood , well-being 1 month treatment, , had long-lasting preventive effect on relapse drug use. in 16-month follow-up, relapse rates of prasterone-treated subjects 11.5%. no adverse symptoms found. these findings demonstrate long-term effect of prasterone on drug relapse.

lupus

there evidence of short-term benefit in systemic lupus erythematosus little evidence of long-term benefit or safety.

memory

prasterone supplementation has not been found useful memory function in normal middle aged or older adults. has been studied treatment alzheimer s disease, there no evidence effective.

mood

a few small, short term clinical studies have found prasterone improves mood long-term efficacy , safety, , how compares antidepressants, unknown of 2015.

strength

evidence inconclusive in regards effect of prasterone on strength in elderly.

in middle-aged men, no significant effect of prasterone supplementation on lean body mass, strength, or testosterone levels found in randomized placebo-controlled trial.