CREB complex Deficiency of RbAp48 protein and memory loss

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creb (top) transcription factor capable of binding dna (bottom) , regulating gene expression


creb-binding protein, known crebbp or cbp, protein encoded crebbp gene in humans.


the creb protein carries out function activating transcription, interaction transcription factors managed 1 or more creb domains: nuclear receptor interaction domain (rid), creb , myb interaction domain (kix), cysteine/histidine regions (taz1/ch1 , taz2/ch3) , interferon response binding domain (ibid). creb protein domains, kix, taz1 , taz2, each bind tightly sequence spanning both transactivation domains 9aatads of transcription factor p53.








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